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Acetaminophen Dextromethorphan Hbr Guaifenesin Phenylephrine Hcl and Acetaminophen Dextromethorphan Hbr Doxylamine Succinate Phenylephrine Hcl

OTC RxCUI 1297288
Contents

Overview

Label date
2026-03-26

Indications and usage

Uses temporarily relieves: - nasal congestion - headache - cough - minor aches and pains - sinus congestion and pressure - runny nose and sneezing (NIGHTTIME only) helps loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bothersome mucus and make coughs more productive. ( DAYTIME only)

Purpose

s Daytime Sinus Relief Pain reliever Cough suppressant Expectorant Nasal decongestant Purposes Nighttime Sinus Relief Pain reliever Cough suppressant Antihistamine Nasal decongestant

Dosage and administration

Directions do not take more than directed (see Overdose warning) do not take more than 12 softgels in any 24-hour period adults and children 12 years of age and older: take 2 softgels every 4 hours children under 12 years of age: do not use

Warnings

Liver warning: This product contains acetaminophen. Severe liver damage may occur if you take: more than 12 softgels in 24 hours, which is the maximum daily amount with other drugs containing acetaminophen 3 or more alcoholic drinks every day while using this product Allergy alert: Acetaminophen may cause severe skin reactions. Symptoms may include: skin reddening blisters rash If a skin reaction occurs, stop use and seek medical help right away.

Do not use

with any other drug containing acetaminophen (prescription or nonprescription). If you are not sure whether a drug contains acetaminophen, ask a doctor or pharmacist. if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug. If you do not know if your prescription drug contains an MAOI, ask a doctor or pharmacist before taking this product.

Ask a doctor before use if

Ask a doctor before use if you have liver disease heart disease diabetes high blood pressure thyroid disease trouble urinating due to an enlarged prostate gland glaucoma ( NIGHTTIME only ) breathing problems such as emphysema or chronic bronchitis ( NIGHTTIME only ) persistent or chronic cough such as occurs with smoking, asthma, chronic bronchitis, or emphysema cough that occurs with too much phlegm (mucus)

Ask a doctor or pharmacist before use if

Ask a doctor or pharmacist before use if you are taking the blood thinning drug warfarin taking sedatives or tranquilizers ( NIGHTTIME only )

When using this product

this product do not use more than directed excitability may occur, especially in children ( NIGHTTIME only ) marked drowsiness may occur (NIGHTTIME only) alcohol, sedatives, and tranquilizers may increase drowsiness (NIGHTTIME only) avoid alcoholic drinks (NIGHTTIME only) be careful when driving a motor vehicle or operating machinery (NIGHTTIME only)

Stop use and ask a doctor if

and ask a doctor if nervousness, dizziness, or sleeplessness occur pain, nasal congestion, or cough gets worse or lasts more than 7 days fever gets worse or lasts more than 3 days redness or swelling is present new symptoms occur cough comes back, or occurs with fever, rash, or headache that lasts. These could be signs of a serious condition.

Pregnancy or breast-feeding

If pregnant or breast-feeding, ask a health professional before use.

Active ingredient (label)

s (in each softgel) Daytime Sinus Relief Acetaminophen 325 mg Dextromethorphan HBr 10 mg Guaifenesin 200 mg Phenylephrine HCl 5 mg Active ingredients (in each softgel) Nighttime Sinus Relief Acetaminophen 325 mg Dextromethorphan HBr 10 mg Doxylamine succinate 6.25 mg Phenylephrine HCI 5 mg

Inactive ingredients

s (DAYTIME only) FD&C yellow no. 6, gelatin, glycerin, polyethylene glycol, povidone, propylene glycol, shellac, sorbitol sorbitan solution, titanium dioxide, purified water. Inactive ingredients (NIGHTTIME only) FD&C blue no. 1, gelatin, glycerin, polyethylene glycol, povidone, propylene glycol, shellac, sorbitol sorbitan solution, titanium dioxide, purified water

Keep out of reach of children

of children. Overdose warning: Taking more than the recommended dose (overdose) may cause liver damage. In case of overdose, get medical help or contact a Poison Control Center right away (1-800-222-1222). Quick medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms.